Bag Syndrome (PUBS) is an uncommon condition that is related with a generally normal sickness process: bacterial urinary plot disease. Some critical situation like urinary leakage, urinary retention , surgery that made a urinary drain bag necessary.
Ordinarily, PUBS is related with gram-negative UTIs, however requires specific conditions to happen. It is most often found in older, sick females (however it additionally happens in guys) who will generally be constantly siphoned and blocked up. Patients with ileal redirections have additionally been accounted for to foster this condition.
A Urinary Drain Bag
It is felt that stoppage inclines patients toward this condition as it advances bacterial excess and this high bacterial burden has a significant impact of the pathophysiology. This adjustment of gastrointestinal verdure permit dietary tryptophan to be utilized to indole, which is hence used to indoxyl sulfate in the liver. This compound is then discharged in the pee where the microbes causing the contamination catalyze the change of indoxyl sulfate into indoxyl. In basic conditions, the indoxyl is then additionally changed over to the pigmented intensifies indigo blue and indirubin, which join to add to the purple staining (See grouping underneath).
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from diagram initially distributed in Purple Urine Bag Syndrome: A Rare and Interesting Phenomenon. South Med J. 2007;100(10):1048-1050.
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from diagram initially distributed in Purple Urine Bag Syndrome: A Rare and Interesting Phenomenon. South Med J. 2007;100(10):1048-1050.
Microbial science
Microbes generally filled in the pee culture of patients with PUBS incorporate Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Enterococcus species, Pseudomonas aeruginosa, Citrobacter species, and a few others.
Treatment
While outwardly disturbing, the purple staining is genuinely harmless and the board spins around treatment of the hidden condition. Most frequently, fruitful treatment of the UTI and trade of the catheter regularly settle the condition.
Case Resolution
The pee culture grew 100,000 settlements of Proteus mirabilis vulnerable to ceftriaxone. The patient was in the long run released home on emergency clinic day #3 with cephalexin for 14 days.
Bring Home Points
Bars is an interesting show of urinary parcel contamination predominately in old with a background marked by blockage and ongoing catheterization
The pathophysiology of
PUBS isn't totally seen however is connected with bacterial abundance in the stomach and change of tryptophan to urinary shades through an intricate series of responses
The administration of PUBS is centered around treatment of the basic urinary lot condition which incorporates anti-infection treatment covering the fitting microflora and foley
catheter trade if material
